Mendoza Wine Region Vacations from $278

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Mendoza Wine Region vacation packages

Price found within the past 48 hours. Click for updated prices.
Condor Suites Apart Hotel

Condor Suites Apart Hotel

Mendoza City Center
Save 100% on your flight
$278
per person
Oct 25 - Oct 30
found 20 hours ago
Roundtrip flight included
Buenos Aires (AEP) to Mendoza (MDZ)
8.4/10 Very Good! (227 reviews)
Good value for money. Centrally located, safe and clean. Spacious room, good breakfast and responsive staff. I would stay here again if I am to travel back to Mendoza.

Reviewed on Jun 22, 2026

Rosell Boher Winery Lodge & Spa

Rosell Boher Winery Lodge & Spa

$636
per person
Sep 14 - Sep 17
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Mendoza (MDZ)
9.4/10 Exceptional! (172 reviews)
This was the absolute dreamiest weekend in Mendoza I could’ve ever imagined. The property is stunning, the villa is extraordinary! The service is phenomenal and thoughtful and helpful and kind, the food is incredible. And the wine! Every single detail for every moment had the utmost care and attention. I can not rave enough about how wonderful this place and staff are. It’s extraordinary!

Reviewed on Jul 19, 2026

La María Hotel Boutique

La María Hotel Boutique

Save 100% on your flight
$1,044
per person
Oct 25 - Oct 30
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Mendoza (MDZ)
10/10 Exceptional! (56 reviews)
This is a jewel of a hotel. Probably one of the most beautiful and comfortable in which I’ve ever stayed. The rooms are spectacular. We had a private sauna, steam shower and hot tub, along with a bedroom and sitting area. The hosts are charming and the food delicious.

Reviewed on Jun 20, 2026

Uvas Apart Hotel

Uvas Apart Hotel

Mendoza City Center
$285
per person
Oct 25 - Oct 30
found 20 hours ago
Roundtrip flight included
Buenos Aires (AEP) to Mendoza (MDZ)
8/10 Very Good! (73 reviews)
Fantastic value for the apartment you get. It's a "hotel" in terms of being staffed/having amenities, but it's not your normal hotel. It's a fully furnished apartment. Very, very comfortable stay. If I were going back to Mendoza, I'd immediately book here again, without thinking twice. Highly recommend!!!

Reviewed on Apr 26, 2026

Park Hyatt Mendoza

Park Hyatt Mendoza

Mendoza City Center
Save 100% on your flight
$615
per person
Oct 25 - Oct 30
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Mendoza (MDZ)
9.2/10 Wonderful! (1,004 reviews)
Don't see what you're looking for?
See all available trips from Columbus to Mendoza Wine Region
View all trips

Where to stay in Mendoza Wine Region

Find the best Mendoza Wine Region areas and neighborhoods for the activities you enjoy most. Learn more about Mendoza Wine Region
A large, multi-level auditorium with red seating and multiple balconies.

Mendoza City Center

6 out of top 10 points of interest in this area

Wineries, casinos, and spas highlight some notable features of Mendoza City Center. Make a stop by Plaza Italia or Independence Square while you're visiting, and jump aboard the metro at Mendoza Station or Belgrano Station to get around town.

A park with fountains, a tower, and people walking.

Historic Center

Sip on a glass of Malbec while people-watching from café-lined squares, catch theater performances, browse art exhibitions and visit striking religious landmarks.

A dirt road leading to a mountain range with a clear sky.

Godoy Cruz

The restaurants and wineries are just a few things visitors like about Godoy Cruz. Avenida San Martin and General San Martin Park are worthwhile spots to check out, and you can hop on the metro at San Martin Station or Pellegrini Station to get around the larger area.

A statue on a rock pedestal surrounded by greenery and a few people.

La Quinta

La Quinta might not have many top sights, but Plaza Italia and Independence Square are two attractions nearby that you can check out.

A vineyard with rows of grapevines in the foreground and snow-capped mountains in the background.

General Gutiérrez

While there might not be top attractions in General Gutiérrez, you can explore the larger area and discover places like National Museum of Wine and Arena Maipu.

Stay near popular Mendoza Wine Region attractions

A snow-capped mountain range, a field of green crops, and a line of trees.

Catena Zapata Winery

9.4/10 (73 reviews)
Taste award-winning wines and tip your glass to the Catena family at one of the world’s leading wineries, famous for its high altitude and Malbec vintages.
See properties
A fountain with multiple water jets, surrounded by a stone wall with sculptures, set in a park with trees and a clear blue sky.

Independence Square

8.8/10 (408 reviews)
Visit Mendoza’s cultural heart to see museums and basilicas or simply sit in the shade with an ice cream and watch the entertainment in the plaza.
See properties
A large stone monument with a relief sculpture of a man and a woman, surrounded by a mosaic depicting historical scenes.

Spain Square

9.0/10 (286 reviews)
Unwind in one of Mendoza’s most beautiful public squares, given to Argentina by the Spanish government.
See properties
A large statue on a pedestal with steps leading up to it, surrounded by trees and a clear blue sky.

General San Martin Park

9.2/10 (423 reviews)
Walk or cycle around this expansive park to see the glistening lake, pay your respects at the war memorials and enjoy a great view of the city.
See properties
A fountain in a park with tall buildings in the background.

Plaza Italia

8.8/10 (314 reviews)
Find a quiet place to enjoy a siesta in this peaceful park, complete with a playground and a monument to the city’s Italian heritage.
See properties

Cacheuta Thermal Springs

8.6/10 (97 reviews)
Commune with nature and explore the great outdoors at Cacheuta Thermal Springs during your travels in Cacheuta. While in this relaxing area, you can enjoy the wineries.
See properties

Avenida San Martin

8.8/10 (321 reviews)
During your trip to Mendoza, you can do some window-shopping at Avenida San Martin. Visit the area's casinos and spas.
See properties

Bodega Salentein

9.2/10 (24 reviews)
You can enjoy a tasting or tour at Bodega Salentein during your travels to Los Árboles. You can enjoy the wineries while in the area.
See properties

What to do in Mendoza Wine Region

From Mendoza: High Andes Aconcagua Mountain Tour

From Mendoza: High Andes Aconcagua Mountain Tour

$68
per adult
From Mendoza: High Andes Aconcagua Mountain Tour
High Mountain and Inca Bridge

High Mountain, Aconcagua and Inca Bridge

$65
per adult
High Mountain, Aconcagua and Inca Bridge
Mendoza: 12-KM River Rafting Tour in the Andes

Mendoza: 12-KM River Rafting Tour in the Andes

$35
per adult
Mendoza: 12-KM River Rafting Tour in the Andes
See all activities in Mendoza Wine Region

Mendoza Wine Region Hotel Deals

Park Hyatt Mendoza

Park Hyatt Mendoza

Chile 1124 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$221 nightly
$221 total
Aug 24 - Aug 25
Park Hyatt Mendoza
Sheraton Mendoza Hotel

Sheraton Mendoza Hotel

Primitivo De La Reta 989 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$160 nightly
$160 total
Aug 14 - Aug 15
9.2/10 Wonderful! (1,000 reviews)
"Good size room"

Reviewed on Jul 29, 2026

Sheraton Mendoza Hotel
Diplomatic Hotel

Diplomatic Hotel

Belgrano 1041 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$182 nightly
$182 total
Aug 28 - Aug 29
9.4/10 Exceptional! (1,000 reviews)
"Top notch service. Very clean. Nice complimentary buffet breakfast."

Reviewed on Jul 28, 2026

Diplomatic Hotel
See all 1,048 properties in Mendoza Wine Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mendoza Wine Region Vacation Packages

Mendoza Wine Region Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Governor Francisco Gabrielli Intl. Airport (MDZ)
Population
876,900

More vacations you might like

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.